El Dr. Luis Larrondo estudió Bioquímica y realizó su doctorado en Biología Celular y Molecular en la Pontificia Universidad Católica de Chile. Tras un postdoctorado como becario Pew en Dartmouth College, regresó a la UC en 2009, donde actualmente se desempeña como Profesor Titular. Desde 2018 dirige el Instituto Milenio de Biología Integrativa (iBio). Fue International Scholar del HHMI y es actualmente Miembro Asociado de EMBO. Su laboratorio se enfoca en comprender los mecanismos moleculares de los relojes circadianos, con especial énfasis en el rol de la fosforilación, la actividad de CK1 y la función de dominios intrínsecamente desordenados en la generación de ritmos de 24 horas. Su grupo también investiga el impacto de la luz en los programas transcripcionales de hongos y, mediante optogenética y biología sintética, desarrolla circuitos capaces de iniciar y sostener comportamientos oscilatorios, así como módulos genéticos sintéticos para reprogramar la expresión génica. Más recientemente, ha extendido su investigación hacia la relevancia evolutiva y ecológica de los relojes circadianos, explorando los roles mecanísticos de CK1 en diversos sistemas oscilatorios.

Dr. Fernando Danilo González Nilo (Ph.D. in Chemistry, h-index: 40) is a Full Professor and Director of the Center for Bioinformatics and Integrative Biology (CBIB) at Universidad Andrés Bello. He leads an interdisciplinary research team combining high-performance computing with experimental labs (Biophysics, Protein Engineering, Chemical Synthesis) to advance bionanotechnology and drug discovery. With over 170 peer-reviewed articles, 12 journal covers, and 3 granted patents, his research focuses on AI-driven molecular dynamics of ion channels and hemichannels, nanobody engineering, and nanobubble applications across health, agroindustry, and mining.

Cesar Ramirez-Sarmiento is an Associate Professor at the Institute for Biological and Medical Engineering from Pontifical Catholic University of Chile in Santiago, Chile. He is also co-founder and scientific advisor of the Chilean startup NexEnzymes and the ReClone network, both of which focus on locally manufacturing molecular kits for research and diagnostics under an open science framework. Cesar is an member of the Frontiers of Science Prograom fromt the Chilean Academy of Sciences, an EMBO Global Investigator since 2023 and a TED Fellow since 2025. His research focuses on the enigmatic class of metamorphic proteins, on the discovery, engineering and design of plastic-degrading enzymes, and the development of new deep-learning tools to study protein structures.

Marcelo Mendoza is an associate professor in the Computer Science Department at Pontificia Universidad Católica de Chile. He received a Ph.D. in Computer Science from the Universidad de Chile. He did a postdoc in Yahoo Research. He is a founder and former President of the Chilean Association of Pattern Recognition. He is a principal researcher at the National Center of Artificial Intelligence (CENIA) and associate researcher at the Millennium Institute for Foundational Research on Data (IMFD). His research is focused on developing AI methods to measure and predict events and processes involving humans. His work includes the study of information dissemination, the spatial distribution of humans within cities, community formation, and the analysis of constructive and destructive interactions among individuals. His contributions are significant in advancing the understanding of how AI can address complex societal challenges, particularly those related to the dynamics of human behavior. He has published over 100 peer-reviewed papers in conference proceedings and top-tier journals. In 2021, he received the Seoul Test of Time award for co-authoring the paper Information Credibility on Twitter, a pioneering study in applying AI to the analysis of misinformation.

Computational Biologist. Professor and researcher at the Institute for Genetics - National University of Colombia, Director of the Bioinformatics and Systems Biology Laboratory and the Data Analysis Service , and Coordinator of the Master’s Program in Bioinformatics in the Department of Systems Engineering. His research focuses on computational modeling of cellular metabolism and the microbiome, with the aim of advancing understanding in precision medicine and nutrition

Giulia Palermo earned her PhD from the Italian Institute of Technology, Genoa, followed by postdoctoral fellowship at the University of California San Diego. She established her lab at the University of California Riverside and has recently moved to the University of California Los Angeles, where she is a Full Professor in the Department of Chemistry and Biochemistry. Her group has pioneered computational studies of CRISPR-Cas9 systems, pushing the boundaries of computational biophysics and developing integrative multiscale approaches that bridge molecular dynamics, quantum mechanics, and cryo-EM modeling with emerging AI methodologies. Using these strategies, the Palermo lab aims to enable computers and AI to model, predict, and guide the function of DNA- and RNA-editing systems. Dr. Palermo is a Camille Dreyfus Teacher-Scholar and has received several honors, including the Corwin Hansch Award for Outstanding Scientists Under 40, the NSF CAREER Award, and the Sloan Research Fellowship in Chemistry.

Clara is a Licensed pharmacist from the University of Kiel. In 2017 she obtained her PhD in Pharmacy in the University of Bonn, where she worked at the laboratory of Christa E. Müller. Afterwards, she worked as a Post-doc researcher at the laboratory of Jens Meiler and James E. Crowe, Jr. at Vanderbilt University.

In 2021 she was incorporated at the Leipzig University as Junior Research Group Leader at the Institute of Drug Discovery in the Faculty of Medicine, and since 2023 Clara is part of the development of novel immunotherapeutic drugs in the same institution as Junior-Professor.

Georg A. Holländer is a physician-scientist specialising in molecular and developmental immunology. His research examines how the thymus develops, functions, ages and regenerates, focusing on the mechanisms through which thymic epithelial cells direct T-cell differentiation, selection and central immune tolerance. His laboratory investigates thymic epithelial lineage specification, stromal–immune interactions, and the transcriptional and epigenetic programmes that govern thymus organogenesis and function. A particular focus is the master transcription factor FOXN1 and its role in regulating chromatin accessibility, epithelial-cell differentiation and the formation of a microenvironment capable of supporting T lymphopoiesis. This work integrates genetic models with single-cell genomics, spatial transcriptomics, epigenomics, advanced imaging and organoid systems. Georg Holländer trained in paediatrics and experimental immunology in Switzerland and the United States and held academic positions at Harvard Medical School and the University of Basel. He is Medical Director of the Botnar Institute of Immune Engineering and holds professorships at the University of Oxford, the University of Basel and ETH Zurich. His broader aim is to translate developmental immunology and immune engineering into improved strategies for diagnosing, preventing and treating diseases affecting children and young people.

Janine Santos, PhD is a molecular geneticist whose research integrates high-throughput screening, genomics, transcriptomics, epigenomics, and other large-scale biological datasets to uncover mechanisms underlying environmental influences on human health. Her work focuses on understanding how mitochondria serve as both targets of exposures and key drivers of cellular responses that contribute to disease.

I completed my PhD and postdoctoral studies in Bioinformatics at the Structural Bioinformatics Group of the University of Quilmes. I created the outreach project "Bioinformatics Goes to School" and founded the Latin American Community of Women in Bioinformatics and Data Science. Currently, I work as a CONICET researcher studying the conformational diversity of protein cavities to improve techniques for predicting protein-ligand interactions.

Janin Riedelsberger is an Assistant Professor in the Department of Bioinformatics at the University of Talca, Chile. She earned her Diploma in Biology from the University of Potsdam, Germany, in 2009, and completed her PhD at the Max Planck Institute of Molecular Plant Physiology in collaboration with the University of Potsdam in 2013. Following postdoctoral research in Chile, she joined the tenure-track faculty at the University of Talca in 2017.
She actively contributes to student education and research mentorship within both the undergraduate Bioinformatics program and the PhD program in Modeling of Chemical and Biological Systems. Her research group investigates ion channels and sugar transporters, focusing on the relationship between structure and function. The work is distinguished by its integration of computational and experimental approaches, combining techniques such as comparative modeling, molecular dynamics, docking, molecular biology, and electrophysiology.

Wendy González is a full professor at the University of Talca, Chile. She received her Ph.D. from this university in 2010. Later, she conducted postdoctoral research at Universität Potsdam, Germany (2010-2012). During her PhD. and postdoctoral research, she used molecular modeling and molecular dynamics simulations to understand ion channels behavior. At the end of 2012, she became the Director of the Center for Bioinformatics, Simulation and Modelling (CBSM) at the University of Talca, Chile. The focus of her research is protein molecular modeling, mainly ion channel modeling and their interactions with drugs.

Alex Di Genova es Ingeniero en Bioinformática de la Universidad de Talca y Doctor en Ingeniería de Sistemas Complejos de la Universidad Adolfo Ibáñez. La línea de investigación del Dr. Di Genova se centra en el desarrollo de nuevos algoritmos para el análisis de datos genómicos. El Dr. Di Genova ha publicado más de 30 artículos científicos en revistas ISI, ha participado en proyectos genómicos nacionales e internacionales y ha contribuido dos programas de código abierto para ensamblar secuencias genómicas. Actualmente el Dr. Di Genova está desarrollando nuevos métodos y algoritmos computacionales para caracterizar reordenamientos genómicos en distintos tipos de cáncer humano, con el objetivo de comprender como estos procesos mutacionales contribuyen en la progresión y evolución de esta enfermedad.

En el Instituto de Ciencias de la Ingeniería, Alex Di Genova participa en el área de Biología computacional y Biotecnología.

Gabriel Cabas is a Bioinformatics Engineer working at the interface of artificial intelligence, genomics, epigenomics, and computational pathology. His work focuses on developing machine learning and deep learning approaches to extract biological insight from large-scale omics datasets and histological images.
He is particularly interested in genomic prediction, genome-wide association studies, polygenic risk modeling, and AI-driven analysis of tissue architecture. His research contributes to the development of data-driven tools for understanding complex disease mechanisms and advancing precision medicine in research and clinical settings.

Noemí Gómez is a Bioinformatics Engineer and PhD student in Bioengineering at Universidad de O’Higgins. At Di Genoma Lab, she works on computational cancer biology, integrating transcriptomic, epigenomic, histological, clinical, and ancestry-related data to study tumor heterogeneity in prevalent Chilean cancers, especially gallbladder and colorectal cancer.

Her research combines multi-omics integration, trade-off modeling, and evolutionary perspectives to identify molecular tumor states and genotype-phenotype relationships. She is also interested in using artificial intelligence to infer molecular features directly from histopathology images, with the goal of building more representative cancer models for Chilean and Latin American populations.

Alberto J. M. Martin es biólogo computacional y académico de la Universidad San Sebastián/Fundación Ciencia & Vida, donde dirige el Doctorado en Biología Computacional. Su línea de trabajo integra machine learning, redes biológicas y análisis ómico/single-cell para estudiar mecanismos regulatorios en sistemas biológicos complejos.

El Dr. Jesús Espinal Enríquez es uno de los investigadores mexicanos que ha contribuido de manera más consistente al desarrollo de la biología de sistemas aplicada al cáncer. Su trabajo ha permitido comprender cómo la organización funcional de la expresión génica influye en la heterogeneidad tumoral y ha dado lugar a metodologías innovadoras basadas en redes de coexpresión específicas de cada paciente para el descubrimiento de biomarcadores con valor diagnóstico, pronóstico y predictivo. Más recientemente, ha integrado estas aproximaciones con inteligencia artificial para desarrollar herramientas de oncología de precisión orientadas a la selección personalizada de tratamientos.

Genomic diversity has shaped phenotypes that are linked to environmental adaptation and disease, deciphering these associations has been the main goal of my research. I obtained a PhD in Biology in 2000 at the Barcelona University by studying the molecular basis of thrombophilia. From 2000 to 2003 I performed a postdoctoral stage at the University Paris V (France), awarded with a Marie Curie fellowship, where I focused on the study of syndromic disorders using genomic and transcriptomic approaches. In 2004 I gained a competitive position and became an independent researcher with a “Ramón y Cajal” contract at the Center for Genomic Regulation -CRG in Barcelona, there I had the opportunity to lead my own research group studying the role of microRNA-meditated regulation in disease. In 2009 I entered the Universitat Pompeu Fabra in Barcelona as Associate Professor, continuing with the study of gene regulation and disease but under the perspective of evolution. In 2015 I moved to Punta Arenas (Chile), with the aim contribute to the scientific development of the southernmost region in America, there I have a position as Full Professor at the Medicine School in the Magallanes University where I have been working in the establishment of a pool of research at the Center for Education, Healthcare and Investigation (CADI), where I lead a research group GEMMa “Genomica Evolutiva y Médica de Magallanes”, focusing on Evolutionary Genomic Medicine. I have published 46 articles in indexed journals (22 as first, last or CA) with an H index of 25 and I have an important track of scientific communications at international meetings, and participation as speaker in several symposiums.

El Dr. Alexis Salas-Burgos es Profesor Asociado del Departamento de Farmacología de la Facultad de Ciencias Biológicas de la Universidad de Concepción, Chile. Es Bioquímico y Doctor en Ciencias Biológicas, mención Biología Celular y Molecular, por la Universidad de Concepción. Su trayectoria científica integra farmacología, biología molecular y computacional, bioinformática y oncología, con énfasis reciente en comprender los mecanismos moleculares asociados a la progresión del cáncer, el microambiente tumoral y la heterogeneidad de la enfermedad. Actualmente desarrolla proyectos de progresión oncológica asociados a la proresión de cáncer digestivos, remodelación metabolómica, sistema inmune en progresión oncológica, exposoma y la interesección entre enfermedaes de baja frecuencia y oncología para diseño de terapias.

El Dr. Gonzalo Jaña Villalobos es químico y Doctor en Ciencias con mención en Química por la Universidad de Concepción. Actualmente es Profesor Asociado del Departamento de Ciencias Químicas de la Facultad de Ciencias Exactas de la Universidad Andrés Bello, sede Concepción. Su investigación se desarrolla en el área de la química computacional y el diseño molecular, con énfasis en la elucidación de mecanismos de reacción en sistemas de interés biológico. Para ello integra métodos de acoplamiento molecular, dinámica molecular, cálculos de estructura electrónica y simulaciones híbridas QM/MM, orientadas a caracterizar procesos de reconocimiento molecular, catálisis enzimática e inhibición covalente. Su trabajo actual se centra en el estudio de la telomerasa humana como blanco de interés oncológico, particularmente en la caracterización del mecanismo de inhibición por compuestos reactivos con cisteína. En esta línea, investiga la unión y formación del aducto covalente entre chrolactomycin y hTERT mediante una estrategia multiescala que conecta el docking, la dinámica molecular y los perfiles de energía libre obtenidos mediante QM/MM. caracterización del mecanismo de inhibición por compuestos reactivos con cisteína. En esta línea, investiga la unión y formación del aducto covalente entre chrolactomycin y hTERT mediante una estrategia multiescala que conecta el docking, la dinámica molecular y los perfiles de energía libre obtenidos mediante QM/MM.

Dr. Maricel Kann is an Associate Professor at the University of Maryland, Baltimore County where she has been since 2007. She received a B. Sc. degree from the Universidad de la Republica in Montevideo (Uruguay) and a PhD degree in Chemistry from the University of Michigan (Ann Arbor). Afterwards, she joined the Structure group at the NCBI (NIH) as a postdoctoral fellow. Dr. Kann's research focuses on developing new computational methodologies to identify the role of individual cancer and other disease mutations in the disease mechanisms.

She is one of the leading experts in the area of translational Bioinformatics and has chaired and cochaired several international conference sessions (PSB, AMIA, ISMB). She was a committee member of the Annual Review of Biomedical Data Science, an associate editor of the Journal of Computational Biology and PLoS computational Biology, and a current member of the NIH/NLM Scientific Board. She was also a past member of the NIH/NLM study review session, advisory board of the PubMedCentral National Committee and of the scientific advisory board of the UniProt consortium.

La Dra. Valentina González-Pecchi es Profesora Asistente del Departamento de Ciencias Básicas de la Facultad de Medicina de la Universidad Católica de la Santísima Concepción (UCSC), Chile. Obtuvo su grado de Doctora en Biología del Cáncer en Emory University y lidera una línea de investigación enfocada en comprender los mecanismos moleculares que regulan la señalización oncogénica en cáncer. Su investigación integra enfoques de biología celular, biología molecular y biología química para identificar nuevas dianas terapéuticas y descubrir moléculas pequeñas capaces de interferir en interacciones proteína–proteína involucradas en la progresión tumoral.

Participa activamente en la formación de estudiantes de pregrado y postgrado, así como en la mentoría de jóvenes científicos. Además, forma parte del Directorio Ejecutivo de la Sociedad de Bioquímica y Biología Molecular de Chile (SBBMCh), contribuyendo a la promoción de la investigación en bioquímica y biología molecular y al fortalecimiento de la colaboración científica a nivel nacional.